Our Research Aims

Our research program has two broad scientific aims, each addressed through the work of three integrated work packages:

Aim 1: Map the colorectal cancer microbiome

Work Package 1: The microbiome in cancer risk.

Work Package 2: Epidemiological correlates of the colorectal cancer microbiome.

Work Package 3: Mapping the cellular distribution of the colorectal cancer microbiome. 

Aim 2: Understand the clinical impact of modulating the colon cancer microbiome

Work Package 4: Model systems to study the colorectal cancer microbiome.

Work Package 5: The interplay between the microbiota and colorectal cancer treatments. 

Work Package 6: Novel treatments involving microbiome modulation. 

We also have a public-facing objective: to share and disseminate our data, methodologies and concepts with the scientific, medical and patient communities. 

This integrated structure of our program is illustrated in the figure on the right.