OPTIMISTICC
Opportunity To Investigate the Microbiome’s Impact on Science and Treatment In Colorectal Cancer
We are an international team working together to understand the colorectal cancer microbiome: what it is, how it is associated with cancer, and what treatments will affect the microbiome to promote health.
Our objectives are to:
- Map the colorectal cancer microbiome
- Develop microbiome-targeted therapies for colorectal cancer
- Share and disseminate our findings
Colorectal Cancer Awareness Month
Read our advocate stories to learn more about the signs and symptoms of colorectal cancer.

We are our microbes!
Watch the video that explains what the microbiome is and the importance in colorectal cancer. This video was a collaboration between team OPTIMISTICC patient advocates and researchers. Get ready to learn and ENJOY!
Watch the OPTIMISTICC Webinar
A series of informal conversations between the OPTIMISTICC researchers and patient advocates discussing the role of the gut microbiome in human health and disease and its association with colorectal cancer.
This webinar is a collaboration between Colorectal Cancer Canada, the OPTIMISTICC team, and the Cancer Research UK Cancer Grand Challenges.
What’s new
Western Diet and CRC
In a recent publication Kota Arima and other OPTIMISTICC team members published a paper Western-Style Diet, pks Island-Carrying Escherichia coli,...
New review about colorectal cancer and the microbiome
In a recent review by Slater Clay and other OPTIMISTICC team members, titled Colorectal cancer: the facts in the case of the microbiota they review...
Colorectal Cancer and the Microbiome Webinar
Colorectal Cancer & the MicrobiomeIt’s becoming increasingly clear that colorectal cancer – the third most common cancer worldwide – is...

Our Sponsor
OPTIMISTICC is a Cancer Grand Challenges team funded by Cancer Research UK.
Our Partners









