The Giannakis and Ogino labs have published a new study in Cancer Discovery that describes a mutational signature associated with high intake of red meat and increased colorectal cancer mortality. The team analyzed whole exome sequencing and epidemiological data from 900 CRC cases and discovered the alkylating signature, previously undescribed in CRC. Marios discusses this work in an AACR press release. The study was also covered by news organizations around the world; for example, FranceSoir, The Times of India, Aljazeera, and Yahoo News.
Kimmie Ng and Marios Giannakis publish a perspective “A Common Cancer at an Uncommon Age”
By 2030 colorectal cancer will be the leading cause of cancer deaths in individuals aged 20-49. Young-onset CRC differs from average age onset. Young-onset disease is often more aggressive, presents on the left side of the colon rather than the right, and often...