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Biomarker for Locally Advanced Rectal Cancer (LARC) Identified from the Gut Microbiome

July 9, 2020

Biomarker for Locally Advanced Rectal Cancer (LARC) Identified from the Gut Microbiome

July 9, 2020
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A team led by VHIO Principal Investigator and OPTIMISTICC scientist Dr. Paolo Nuciforo has found an association between the persistence of Fusobacterium  nucleatum in rectal tumors of LARC patients after chemotherapy and higher rates of rectal cancer relapse. This discovery, published recently in the Annals of Oncology, indicates that Fusobacterium can serve as a prognostic biomarker that will help physicians better determine and adjust courses of treatment for LARC. This study is described in more detail in VHIO’s press release.

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